EFFECT OF MAINTENANCE DIALYSIS ON LYMPHOCYTE FUNCTION .2. PERITONEAL-DIALYSIS

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 33  (1) , 102-106
Abstract
Lymphocyte function, as assessed by PHA[phytohemagglutinin]-stimulated DNA synthesis, was studied in chronic renal failure patients maintained by peritoneal dialysis. In contrast to patients on hemodialysis, peritoneal dialysis patients had normal lymphocyte responsiveness pre-dialysis. There was no deterioration in the post-peritoneal dialysis plasma''s ability to support control lymphocyte responsiveness as occurred after hemodialysis. Plasma dilution and reconstitution studies indicated that hemodialysis depleted the patients'' plasma of nutrients and also added toxins, but peritoneal dialysis had neither effect.