Pretreatment with alfentanil reduces pain caused by propofol
- 1 March 1994
- journal article
- clinical trial
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 72 (3) , 342-344
- https://doi.org/10.1093/bja/72.3.342
Abstract
We have compared two groups (n = 22) of unpremedicated patients to determine if the pain caused by injection of propofol could be modified by alfentanil. In group I, alfentanil 1 mg was given as a bolus i.v. injection 15 s before administration of propofol i.v., while group II received saline. Propofol was given in 20-mg increments every 4 s. All injections were given through the same i.v. cannula on the dorsum of one hand. We found that alfentanil pretreatment reduced pain on injection of propofol (P = 0.001).Keywords
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