Idoxuridine in Herpesvirus Encephalitis

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Abstract
Although great strides have been made in the development of virus vaccines against some of the major epidemic diseases of man, disappointingly little has been accomplished in the development of antiviral chemotherapy. There are many serious viral illnesses that are not preventable by universal vaccination and probably will not be in the foreseeable future. Herpesvirus encephalitis, the most common cause of sporadic fatal encephalitis in this country, is such a disease. Of 36 patients with this diagnosis recently described by Olson and his associates, 21 died, and all but three survivors had residual effects.1 The illness is characterized by rapid . . .