Association of class I, II, and III MHC gene products with systemic lupus erythematosus
- 1 July 1989
- journal article
- research article
- Published by Springer Nature in Rheumatology International
- Vol. 9 (1) , 13-18
- https://doi.org/10.1007/bf00270284
Abstract
Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was observed. Additional findings were a significantly increased frequency of HLA-B13 and a significant decrease of HLA-B44.Keywords
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