EFFECT OF A SYSTEMICALLY ADMINISTERED PROGESTOGEN ON HISTOPATHOLOGY OF ENDOMETRIAL CARCINOMA
- 1 October 1974
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 81 (10) , 786-790
- https://doi.org/10.1111/j.1471-0528.1974.tb00381.x
Abstract
Summary: In twenty patients, Stage I endometrial carcinoma was diagnosed by curettage and treated with gestonorone caproate given systemically, prior to hysterectomy. The histological appearances of the tumours before and after treatment were compared and were related to the total dose of progestogen given. In general, regression of the tumour was noted together with increase in differentiation, particularly of tumours initially showing some degree of differentiation. The future of progestogens in the treatment of endometrial carcinoma is discussed.Keywords
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