Morphine action in grouped and isolated rats and mice
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 53 (2) , 191-193
- https://doi.org/10.1007/bf00426491
Abstract
The present study determines the analgesic effects of morphine in grouped and isolated rats and mice. Isolated animals developed altered behavioral patterns, including mouse-killing in rats and mutual aggressiveness in mice. The analgesic effect of morphine was tested by tail compression in rats and by the hot plate for mice. Isolated rats developing mouse-killing behavior had a raised pain threshold, while indifferent animals (nonkillers) responded less to morphine. Isolated mice, particularly low aggressors, gave enhanced responses to morphine.This publication has 17 references indexed in Scilit:
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