Role of the C Terminus of Mec1 Checkpoint Kinase in Its Localization to Sites of DNA Damage
- 1 November 2005
- journal article
- Published by American Society for Cell Biology (ASCB) in Molecular Biology of the Cell
- Vol. 16 (11) , 5227-5235
- https://doi.org/10.1091/mbc.e05-05-0405
Abstract
The large protein kinases, ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR), coordinate the cellular response to DNA damage. In budding yeast, ATR homologue Mec1 plays a central role ...Keywords
This publication has 48 references indexed in Scilit:
- Requirement of the Mre11 Complex and Exonuclease 1 for Activation of the Mec1 Signaling PathwayMolecular and Cellular Biology, 2004
- Amino‐terminal domain of ATRIP contributes to intranuclear relocation of the ATR–ATRIP complex following DNA damageFEBS Letters, 2004
- Choreography of the DNA Damage ResponseCell, 2004
- A Novel Protein Activity Mediates DNA Binding of an ATR-ATRIP ComplexJournal of Biological Chemistry, 2004
- Association of Rad9 with Double-Strand Breaks through a Mec1-Dependent MechanismMolecular and Cellular Biology, 2004
- ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanismGenes & Development, 2003
- RPA Phosphorylation in Mitosis Alters DNA Binding and Protein−Protein InteractionsBiochemistry, 2003
- Lcd1p Recruits Mec1p to DNA Lesions In Vitro and In VivoMolecular Cell, 2002
- Chl12 (Ctf18) Forms a Novel Replication Factor C-Related Complex and Functions Redundantly with Rad24 in the DNA Replication Checkpoint PathwayMolecular and Cellular Biology, 2001
- Regulation of RAD53 by the ATM -Like Kinases MEC1 and TEL1 in Yeast Cell Cycle Checkpoint PathwaysScience, 1996