The Issue of Prophylactic Antibiotics prior to Flexible Cystoscopy

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Abstract
Objective: The aim of this study was to determine whether single–dose parenteral antibacterial therapy significantly alters the rate of infection in patients undergoing flexible cystourethroscopy. Patients and Methods: 162 patients were studied prospectively having either received parenteral antibacterial chemoprophylaxis prior to flexible cystourethroscopy or not. Pre– and postprocedure mid stream samples of urine (MSSU) were obtained to objectively evaluate the presence of infection. Results: Gentamicin prophylaxis reduced the rate of post–cystoscopy–positive MSSUs from 21 to 5%. Conclusion: The surprisingly high rate of infection after flexible cystoscopy was significantly reduced by a single dose of gentamicin.

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