More Than We Ever Wanted to Know about Sex — Should We Be Afraid to Ask?

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Abstract
A desire to control the sex of offspring has intrigued aspiring parents since antiquity. Aristotle is said to have rejected the contention of Empedocles that timing of intercourse affected sex ratio.1 In more recent times, many methods of influencing sex ratios have been proposed. Partial differential separation of X and Y-bearing mammalian sperm has been attempted in vitro by density-gradient sedimentation, electrophoresis and immunologic (anti H-Y) absorption.2 Separation is often inconsistent, sometimes species specific and usually no more than 60 to 70 per cent successful.2 In addition, the safety of subjecting human sperm to in vitro manipulations is difficult to . . .

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