The Oxford Grid
- 1 January 1991
- journal article
- research article
- Published by Wiley in Annals of Human Genetics
- Vol. 55 (1) , 17-31
- https://doi.org/10.1111/j.1469-1809.1991.tb00394.x
Abstract
The ‘Oxford Grid’ is a term used to denote a method of displaying homologous loci from two species. It may also be used as a basis for historical inferences relating to co‐ancestry. These uses are discussed with special reference to man and mouse. It is inferred that as few as 30 reciprocal translocations are sufficient to explain the differences defined by the present grid and that the telocentric karyotype, through which the mouse differs from both man and many closely related rodents, including the rat, must have evolved mainly through the formation and suppression of centromeres rather than through pericentric inversions. Mouse and man share the widest distribution of any mammal and their success appears to be related to being omnivorous with behavioural modifications allowing a wide range of habitat.Keywords
This publication has 9 references indexed in Scilit:
- Chromosome maps of man and mouseClinical Genetics, 2008
- Discovery of the Oldest Known Anthropoidean Skull from the Paleogene of EgyptScience, 1990
- Chromosome maps of man and mouse. IVAnnals of Human Genetics, 1989
- Chromosome maps of man and mouse, IIIGenomics, 1987
- Molecular Analysis of a Constitutional X-Autosome Translocation in a Female with Muscular DystrophyScience, 1987
- Pericentric inversion in human chromosome 1 and the risk for male sterility.Journal of Medical Genetics, 1987
- Evolutionary Relationships in the Genus MusPublished by Springer Nature ,1986
- Chromosome maps of man and mouse IIClinical Genetics, 1984
- EVOLUTIONARY RELATIONSHIPS AMONG FIVE SUBSPECIES OF MUS MUSCULUS BASED ON RESTRICTION ENZYME CLEAVAGE PATTERNS OF MITOCHONDRIAL DNAGenetics, 1981