Comparative activity of cefepime, alone and in combination, against clinical isolates of Pseudomonas aeruginosa and Pseudomonas cepacia from cystic fibrosis patients
Open Access
- 1 April 1991
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 35 (4) , 783-784
- https://doi.org/10.1128/aac.35.4.783
Abstract
The comparative in vitro activity and synergy of cefepime were evaluated with clinical isolates of Pseudomonas aeruginosa and Pseudomonas cepacia from cystic fibrosis patients. The activity of cefepime, both alone and in combination, was comparable to those of other antibiotics. The clinical efficacy of cefepime in cystic fibrosis patients merits investigation.Keywords
This publication has 9 references indexed in Scilit:
- Antipseudomonal therapy in cystic fibrosis: Aztreonam and amikacin versus ceftazidime and amikacin administered intravenously followed by oral ciprofloxacinEuropean Journal of Clinical Microbiology & Infectious Diseases, 1989
- Activity of cefepime against ceftazidime- and cefotaxime-resistant gram-negative bacteria and its relationship to beta-lactamase levelsAntimicrobial Agents and Chemotherapy, 1989
- Frequency of in vitro resistance of Pseudomonas aeruginosa to cefepime, ceftazidime, and cefotaximeAntimicrobial Agents and Chemotherapy, 1988
- Controlled trial of aztreonam vs. tobramycin and azlocillin for acute pulmonary exacerbations of cystic fibrosisThe Pediatric Infectious Disease Journal, 1988
- Evaluation of the in vitro activity of BMY-28142, a new broad-spectrum cephalosporinAntimicrobial Agents and Chemotherapy, 1985
- Controlled trial of ceftazidime vs. ticarcillin and tobramycin in the treatment of acute respiratory exacerbations in patients with cystic fibrosisThe Pediatric Infectious Disease Journal, 1985
- Comparison of a new cephalosporin, BMY 28142, with other broad-spectrum beta-lactam antibioticsAntimicrobial Agents and Chemotherapy, 1985
- Antimicrobial activities of BMY-28142, cefbuperazone, and cefpiramide compared with those of other cephalosporinsAntimicrobial Agents and Chemotherapy, 1984
- Ceftazidime in treatment of acute pulmonary exacerbations in patients with cystic fibrosisThe Journal of Pediatrics, 1983