Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins
Open Access
- 1 February 2000
- journal article
- research article
- Published by Elsevier in Journal of Lipid Research
- Vol. 41 (2) , 269-276
- https://doi.org/10.1016/s0022-2275(20)32061-7
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiencyNature Genetics, 1999
- The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier diseaseNature Genetics, 1999
- Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1Nature Genetics, 1999
- Probucol Enhances Selective Uptake of HDL-Associated Cholesteryl Esters In Vitro by a Scavenger Receptor B-I–Dependent MechanismArteriosclerosis, Thrombosis, and Vascular Biology, 1999
- Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levelsJournal of Clinical Investigation, 1999
- ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotesJournal of Lipid Research, 1997
- Increased prebeta-high density lipoprotein, apolipoprotein AI, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein AI transgenes.Journal of Clinical Investigation, 1996
- Human HDL cholesterol levels are determined by apoA-I fractional catabolic rate, which correlates inversely with estimates of HDL particle size. Effects of gender, hepatic and lipoprotein lipases, triglyceride and insulin levels, and body fat distribution.Arteriosclerosis and Thrombosis: A Journal of Vascular Biology, 1994
- Metabolism of High-Density Lipoprotein Apolipoproteins in Tangier DiseaseNew England Journal of Medicine, 1978
- The Theory of Tracer Experiments with 131I-Labelled Plasma ProteinsPhysics in Medicine & Biology, 1957