CCR5 Deficiency Is a Risk Factor for Early Clinical Manifestations of West Nile Virus Infection but not for Viral Transmission
Open Access
- 15 January 2010
- journal article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 201 (2) , 178-185
- https://doi.org/10.1086/649426
Abstract
Background. West Nile virus (WNV) is a neurotropic flavivirus transmitted to humans by mosquito vectors. Homozygosity for CCR5Δ32, a complete loss-ofKeywords
This publication has 25 references indexed in Scilit:
- Maraviroc for Previously Treated Patients with R5 HIV-1 InfectionNew England Journal of Medicine, 2008
- Analysis of Genetic Polymorphisms in CCR5, CCR2, Stromal Cell–Derived Factor–1, RANTES, and Dendritic Cell–Specific Intercellular Adhesion Molecule–3–Grabbing Nonintegrin in Seronegative Individuals Repeatedly Exposed to HIV‐1The Journal of Infectious Diseases, 2004
- Role for CCR5Δ32 Protein in Resistance to R5, R5X4, and X4 Human Immunodeficiency Virus Type 1 in Primary CD4+CellsJournal of Virology, 2004
- Transmission of West Nile Virus through Blood Transfusion in the United States in 2002New England Journal of Medicine, 2003
- Transmission of West Nile Virus from an Organ Donor to Four Transplant RecipientsNew England Journal of Medicine, 2003
- Epidemic West Nile encephalitis, New York, 1999: results of a household-based seroepidemiological surveyThe Lancet, 2001
- The West Nile Virus Outbreak of 1999 in New York: The Flushing Hospital ExperienceClinical Infectious Diseases, 2000
- Phenotypic Expressions of CCR5-Δ32/Δ32 HomozygosityJAIDS Journal of Acquired Immune Deficiency Syndromes, 1999
- Genotype and allele frequency of a 32-base pair deletion mutation in the CCR5 gene in various ethnic groups: Absence of mutation among asians and pacific islandersInternational Journal of Infectious Diseases, 1999
- Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural GeneScience, 1996