MMTV-like env gene sequences in human breast cancer
- 31 January 2001
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 146 (1) , 171-180
- https://doi.org/10.1007/s007050170201
Abstract
We have previously detected an MMTV env gene-like 660 bp sequence in 38% of human breast cancers, but not in normal tissues or other tumors. In this communication we report the sequences from eleven tumors and three breast cancer cell lines, and compare them to four strains of MMTV and to the known endogenous retroviral sequences. The breast cancer sequences were highly homogenous to the MMTV’s, but not to the endogenous sequences suggesting an exogenous origin.Keywords
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