Breast Cancer: Long-Term Tamoxifen Trial Halted

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Abstract
In a blow to a promising treatment for breast cancer, a major trial of long-term treatment with the drug tamoxifen has been halted because of evidence that the drug loses its effectiveness if it is given for more than 5 years. The U.S. National Cancer Institute says more research is needed to determine whether tamoxifen may even increase cancer mortality if given for longer periods.

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