Angiotensin Converting Enzyme (ACE) Ein in vitro-Test f r die Sarkoidose-Diagnostik
- 1 February 1980
- journal article
- research article
- Published by Springer Nature in Klinische Wochenschrift
- Vol. 58 (4) , 195-198
- https://doi.org/10.1007/bf01476778
Abstract
Bei 50 Patienten mit Sarkoidose (39 mit aktiver, 11 mit inaktiver Sarkoidose) wurde das Angiotensin-converting enzyme (ACE) im Serum bestimmt. Die Gruppe der Kontrollpatienten umfaßte 50 Personen (34 mit chronischen Lungenerkrankungen, 9 mit Morbus Hodgkin, 7 mit chronischer Polyarthritis). Der Unterschied der Mittelwerte der ACE-Aktivität war zwischen Sarkoidosepatienten (28,6±11,4) und Kontrollpatienten (14,8±4) hochsignifikant (ppp<0.001). Coricosteroid treatment seems to lower ACE activity in patients with sarcoidosis without offering a clue for clinical improvement. Increased ACE activity in other granulomatous disorders is being discussed. ACE activity thus proves to be a valuable test especially in differentiating active from inactive sarcoidosis.Keywords
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