5-hydroxytryptamine metabolism, superior colliculus, and grooming behavior in cats with pontile lesions.
- 1 January 1973
- journal article
- research article
- Published by American Psychological Association (APA) in Journal of Comparative and Physiological Psychology
- Vol. 85 (1) , 1-10
- https://doi.org/10.1037/h0034856
Abstract
Presents data indicating that the abnormal grooming behavior displayed by cats with pontile lesions, which waxes and wanes during the year, is mediated by serotonergic neurons in the supeior colliculus. Manipulations of 5-hydroxytryptamine metabolism were made systemically, as well as locally in the superior colliculus, in adult male cats with pontile lesions and in normal Ss (N = 40). 5-hydroxytryptophan administration abolished the abnormal behavior, and p-chlorophenylalanine administration induced the abnormal behavior in Ss with pontile lesions; but p-chlorophenylalanine administration to normal Ss did not induce the abnormal behavior. Results indicate that the pontile lesion produces at least 2 critical deficits that induce the abnormal behavior. Previous data indicated that another critical deficit is in glucocorticoid function. (30 ref.) (PsycINFO Database Record (c) 2006 APA, all rights reserved)Keywords
This publication has 0 references indexed in Scilit: