Deficiency of IgG Subclasses and IgA, and Elevation of IgE in Children with a Past History of Bacterial Meningitis

Abstract
Of 44 children who recovered from an attack of bacterial meningitis, 3 (7%) were found to have IgG subclass deficiency, 5 (11%) had IgA deficiency and 22 (50%) had raised IgE levels. These results suggest that immunoglobulin abnormalities may be an important predisposing factor in some cases of bacterial meningitis.

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