Gestational Choriocarcinoma
- 1 January 1972
- journal article
- chemotherapy of-cancer
- Published by S. Karger AG in Oncology
- Vol. 26 (2) , 231-237
- https://doi.org/10.1159/000224671
Abstract
29 patients with trophoblastic tumors of the uterus were evaluated at the University of California, San Francisco. 8 patients admitted before 1956, did not receive chemotherapy; the mortality rate was 87.5%. 21 patients were treated with chemotherapy. The mortality due to disease was 10%. Toxicity was a prominent factor but was completely reversible when chemotherapy was stopped. None of the patients showed recurrent disease during follow-up evaluation 1–12 years after therapy was completed. It is postulated that continuing chemotherapy 4–6 months after clinical remission, and after the chorionic gonadotropin titer, becomes negative, decreases the risk of recurrent disease.Keywords
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