Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells
Open Access
- 1 June 2005
- journal article
- Published by Elsevier in Journal of Lipid Research
- Vol. 46 (6) , 1312-1319
- https://doi.org/10.1194/jlr.m400396-jlr200
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- Apolipoprotein B100 Metabolism in Autosomal-Dominant Hypercholesterolemia Related to Mutations inPCSK9Arteriosclerosis, Thrombosis, and Vascular Biology, 2004
- Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotypeProceedings of the National Academy of Sciences, 2004
- Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed miceJournal of Lipid Research, 2003
- Mutations in PCSK9 cause autosomal dominant hypercholesterolemiaNature Genetics, 2003
- The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiationProceedings of the National Academy of Sciences, 2003
- Normal Production Rate of Apolipoprotein B in LDL Receptor–Deficient MiceArteriosclerosis, Thrombosis, and Vascular Biology, 2002
- Effect of Low-Density Lipoprotein Apheresis on Kinetics of Apolipoprotein B in Heterozygous Familial HypercholesterolemiaJournal of Clinical Endocrinology & Metabolism, 2001
- The role of the LDL receptor in apolipoprotein B secretionJournal of Clinical Investigation, 2000
- The proprotein convertasesCurrent Opinion in Chemical Biology, 1998
- Increased hepatic secretion of very-low-density-lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolaemia: a stable isotope studyAtherosclerosis, 1995