THE RELATIONSHIP BETWEEN PREGNANCY, HCS AND B LYMPHOCYTES

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Abstract
The quantitative distribution of the lymphocyte subpopulations (B [bone marrow-derived], T [thymus-derived] and null) and the serum concentrations of human chorionic somatomammotropin (HCS), IgG [immunoglobulin G], IgM and IgA, the 4th complement component (C4) and C1 inactivator, were estimated in venous blood samples from 32 women at various stages of pregnancy and compared with a control series of 7 non-pregnant normal women. A significant decline in the B cell percentage during pregnancy was seen. The fall in the percentage of the B lymphocytes was concomitant with the rise in HCS concentration. No significant changes in the other parameters studied were present.