Comparison of Analytical Methods in the Determination of Two Venlafaxine Fatalities
Open Access
- 1 March 1997
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 21 (2) , 166-169
- https://doi.org/10.1093/jat/21.2.166
Abstract
Two venlafaxine (Effexor)-related deaths are reported with comparison of results from the analysis of specimens using capillary gas chromatography with a nitrogen-phosphorous detector (GC-NPD) and high-performance liquid chromatography (HPLC) using a UV-vis detector. Blood concentrations in Case 1 were 7.27 µg/mL venlafaxine and 5.03 µg/mL O-desmethylvenlafaxine, and Case 2 had 89.67 µg/mL venlafaxine with 3.44 µg/mL of the desmethyl metabolite. A comparison of analytical methods and specimen concentration is presented.Keywords
This publication has 0 references indexed in Scilit: