Nonalcoholic Fatty Liver Disease
Top Cited Papers
- 18 April 2002
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 346 (16) , 1221-1231
- https://doi.org/10.1056/nejmra011775
Abstract
Alcohol abuse is the most common cause of fatty liver disease, but it is now apparent that fat deposition in the liver, and its consequences, may occur without alcohol abuse. The principal risk factors are obesity, non-insulin-dependent diabetes mellitus, and hyperlipidemia. The disorder has a wide clinical spectrum, ranging from asymptomatic steatosis to steatohepatitis, fibrosis, and cirrhosis. This article provides a broad overview of this increasingly recognized liver disease.Keywords
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