ALKYLATING ACTIVITY OF PROCESSED FISH PRODUCTS TREATED WITH SODIUM-NITRITE IN SIMULATED GASTRIC-JUICE

  • 1 January 1981
    • journal article
    • research article
    • Vol. 72  (3) , 451-454
Abstract
The alkylating activity of extracts from several fish products with or without sodium nitrite in simulated gastric juice was investigated. Some extracts had strong alkylating potency which may be due to the action of the formed N-nitrosamides. These compounds were not derived from nitrosation of methylguanidine and agmatine or from pyrolysis products of the processed fish. A comprehensive investigation of nirosation of various foods in simulated gastric juice is urgently needed. [Diet is regarded as the most important factor in cases of stomach cancer and fish foods may be of major significance in the etiology of human stomach cancer.].

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