Effect of amino acid deprivation and chloramphenicol treatment on cell sizes of rel+ and relA− strains of Escherichia coli
- 1 June 1978
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 24 (6) , 761-764
- https://doi.org/10.1139/m78-127
Abstract
The effects of inhibition of protein synthesis on the cell size distributions of rel+ and relA− derivatives of Escherichia coli K-12 were determined. Amino acid deprivation resulted in a reduction in the cell sizes of rel+ strains but not of relA− strains. Treatment with chloramphenicol (CAM) did not alter the size distributions of either rel+ or relA− strains except when they were rel+dap−. CAM treatment of rel+dap− strains resulted in an increase in cell size. It is proposed that these results reflect differences in the structures of the cell envelopes of rel+ and relA− bacteria.This publication has 5 references indexed in Scilit:
- relA gene control of the synthesis of lipid A fatty acyl moietiesJournal of Bacteriology, 1977
- DNA-dependent in vitro synthesis of ribosomal proteins, protein elongation factors, and RNA polymerase subunit α: Inhibition by ppGppCell, 1976
- Stringent control of peptidoglycan biosynthesis in Escherichia coli K-12Journal of Bacteriology, 1976
- Regulation of membrane phospholipid synthesis by the relA gene: dependence on ppGpp levelsBiochemistry, 1976
- Evidence for a direct effect on fatty acid synthesis in relA gene control of membrane phospholipid synthesisJournal of Molecular Biology, 1976