Selective defect of baroreflex blood pressure buffering with intact cardioinhibition in a woman with familial aniridia
- 1 December 1997
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 49 (6) , 1705-1708
- https://doi.org/10.1212/wnl.49.6.1705
Abstract
We report a symptomatic failure of the baroreceptor blood pressure (BP) buffering mechanism in a woman with familial aniridia. Her baseline BP oscillated at 0.1 Hz, the frequency of Mayer waves, with increased amplitude on standing without orthostatic hypotension. Although sudomotor function was normal, cutaneous thermoregulatory function and BP response to Valsalva9s maneuver were abnormal. The defective BP buffer mechanism suggests Mayer waves could be a sympathetic mediated cardiovascular resonance. Baroreceptor cardioinhibition was intact. We presume that the lesion is in the rostral aspect of the dorsal medulla oblongata.Keywords
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