Splenopentin (DAc SP-5) — Accelerated Reconstitution of Antibody Formation after Syngeneic Bone Marrow Transplantation *)
- 1 January 1989
- journal article
- research article
- Published by Georg Thieme Verlag KG in Experimental and Clinical Endocrinology & Diabetes
- Vol. 94 (04/05) , 219-222
- https://doi.org/10.1055/s-0029-1210901
Abstract
Sublethally irradiated AB/Bln. mice (800 c Gy) and supplemented with syngeneic bone marrow cells were treated with or without a splenopentin derivative (DAc SP-5) and compared for their capacity to produce antibodies. In bone marrow cell plus DAc SP-5 treated animals antibody forming cells were found earlier and in a higher frequency than in mice treated with bone marrow cells only. These findings demonstrate that DAc SP-5 is able to induce bone marrow cell maturation.Keywords
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