Glutathione andγ -glutamyl cycle enzymes in rat mammary gland
- 1 May 1982
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 38 (5) , 531-532
- https://doi.org/10.1007/bf02327032
Abstract
The main enzymes of theγ-glutamyl cycle during the lactogenic cycle in rat mammary gland were studied. A significant increase was found in all of them with the onset of lactogenesis. The effect of methionine sulfoximine on reduced glutathione concentration was studied in tissue slices of lactating mammary gland. The findings suggest that this compound affects glutathione synthesis by inhibitingγ-glutamylcysteine synthetase.This publication has 15 references indexed in Scilit:
- Properties of γ-glutamyltranspeptidase, and glutathione levels in rat mammary glandCellular and Molecular Life Sciences, 1981
- γ-glutamyltranspeptidase activity and cyclic AMP levels in rat liver and mammary gland during the lactogenic cycle and in the oestradiol-progesterone pseudo-induced pregnancyFEBS Letters, 1979
- The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic AgentsAdvances in Cancer Research, 1979
- Glutathione dependent control of protein disulfide-sulfhydryl content by subcellular fractions of hepatic tissueBiochimica et Biophysica Acta (BBA) - General Subjects, 1977
- The activities of the key enzymes of the γ‐glutamyl cycle in microdissected segments of the rat nephronFEBS Letters, 1977
- Glutathione and Related γ-Glutamyl Compounds: Biosynthesis and UtilizationAnnual Review of Biochemistry, 1976
- Intermediates of the gamma-Glutamyl Cycle in Mouse Tissues. Influence of Administration of Amino Acids on Pyrrolidone Carboxylate and gamma-Glutamyl Amino AcidsEuropean Journal of Biochemistry, 1975
- 5-Oxoprolinase from Rat Kidney, I. Assay, Purification, and Determination of Kinetic ParametersHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1975
- Theγ-Glutamyl CycleAnnals of Internal Medicine, 1974
- Isolation of highly purified γ-glutamylcysteine synthetase from rat kidneyBiochemistry, 1971