2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA), an Active Agent in the Resistance of Maize to the European Corn Borer123

Abstract
When 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one was isolated from corn seedlings and bioassayed in an artificial diet for the European corn borer, Ostrinia nubilalis (Hübner), the compound inhibited larval development and caused 25% mortality. These results and associated experimental evidence indicated that the compound is a chemical factor in the resistance of corn to 1st-brood European corn borer. Further, bioassay tests with 6-methoxybenzoxazolinone (MBOA) showed that its biological activity is attenuated by a vitamin combination in which niacin appears to play a key role.

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