The Effect of Directly Observed Therapy on the Rates of Drug Resistance and Relapse in Tuberculosis
- 28 April 1994
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 330 (17) , 1179-1184
- https://doi.org/10.1056/nejm199404283301702
Abstract
Tuberculosis has reemerged as an important public health problem, and the frequency of drug resistance is increasing. A major reason for the development of resistant infections and relapse is poor compliance with medical regimens. In Tarrant County, Texas, we initiated a program of universal directly observed treatment for tuberculosis. We report the effect of the program on the rates of primary and acquired drug resistance and relapse among patients with tuberculosis.Keywords
This publication has 28 references indexed in Scilit:
- Pitfalls in the care of patients with tuberculosis. Common errors and their association with the acquisition of drug resistancePublished by American Medical Association (AMA) ,1993
- Drug resistance of Mycobacterium tuberculosis in KoreaTubercle and Lung Disease, 1992
- Tuberculosis in the United StatesPublished by American Medical Association (AMA) ,1989
- How often is medication taken as prescribed? A novel assessment techniqueJAMA, 1989
- Recurrent tuberculosis: why do patients develop disease again? A United States Public Health Service cooperative survey.American Journal of Public Health, 1988
- Compliance of patients and physicians: experience and lessons from tuberculosis-II.BMJ, 1983
- Controlled trial of 6- and 9-month regimens of daily and intermittent streptomycin plus isoniazid plus pyrazinamide for pulmonary tuberculosis in Hong KongTubercle, 1975
- The problem of self-administration of drugs; with particular reference to pulmonary tuberculosisTubercle, 1958
- OUTPATIENT P.A.S. THERAPYThe Lancet, 1957
- Simple tests for the detection of urinary PASTubercle, 1956