Characterization of IS 6110 Restriction Fragment Length Polymorphism Patterns and Mechanisms of Antimicrobial Resistance for Multidrug-Resistant Isolates of Mycobacterium tuberculosis from a Major Reference Hospital in Assiut, Egypt
Open Access
- 1 June 2001
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 39 (6) , 2330-2334
- https://doi.org/10.1128/jcm.39.6.2330-2334.2001
Abstract
We evaluated 25 Mycobacterium tuberculosis isolates from patients at a major Egyptian reference hospital in Assiut, Egypt, who had been treated for at least 1 year for tuberculosis. Typing patterns (IS6110) were diverse, and multidrug resistance was found among 11 (44%) of the isolates. Mutations associated with antimicrobial drug resistance were found in rpoB, katG, rpsL, and embB in the resistant isolates.Keywords
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