QUALITATIVE CYTOLOGY OF CEREBROSPINAL FLUID AS AN INDICATOR OF NEONATAL BRAIN DAMAGE AND PSYCHOMOTOR OUTCOME
- 1 March 1981
- journal article
- research article
- Published by Wiley in Acta Paediatrica
- Vol. 70 (2) , 161-166
- https://doi.org/10.1111/j.1651-2227.1981.tb05535.x
Abstract
A double blind study was performed on 57 full-term human neonates prospectively subjected to clinical, EEG, CSF and developmental examinations. Usual neonatal pleiocytosis depends on histiomonocytic cells which probably are a reflection of constant small brain damage during delivery. Infants suffering neurological sequelae at age 1 are recognizable as early as the 60th to 84th h of life in view of persisting high histiomonocytic counts (greater than 10 M. elements/l) and granulocytic peaks (greater than 2 M. elements/l) in clear samples. This method is of interest despite its invasive nature and limits (traumatic punctures, time-limits).Keywords
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