Polymorphism of Alcohol Dehydrogenase Genes in Alcoholic and Nonalcoholic Individuals from Valencia (Spain)
Open Access
- 11 May 2004
- journal article
- research article
- Published by Springer Nature in Hereditas
- Vol. 126 (3) , 247-253
- https://doi.org/10.1111/j.1601-5223.1997.00247.x
Abstract
Polymorphisms in the two variable ADHloci (ADH2 and ADH3) were analyzed in two groups (alcoholics and nonalcoholics) from a Spanish population. The frequencies were similar to those reported for other Causcasian groups. ADH2-1 and ADH3-1 genotypes were more frequent in alcoholics than in nonalcoholics, but the differences were not significant.Keywords
This publication has 24 references indexed in Scilit:
- Detection of specific sequences among DNA fragments separated by gel electrophoresisPublished by Elsevier ,2006
- Is Alcohol‐Related Flushing a Protective Factor for Alcoholism in Caucasians?Alcohol, Clinical and Experimental Research, 1995
- Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in chinese patientsHepatology, 1994
- Atypical Liver Alcohol Dehydrogenase in the Spanish Population: Its Relation with the Development of Alcoholic Liver DiseaseAlcohol, Clinical and Experimental Research, 1993
- Absence of the Atypical Mitochondrial Aldehyde Dehydrogenase (ALDH2) Isozyme in Saskatchewan Cree IndiansHuman Heredity, 1993
- The human β3 alcohol dehydrogenase subunit differs from β1 by a cys for Arg-369 substitution which decreases NAD(H) bindingBiochemical and Biophysical Research Communications, 1987
- Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholismHepatology, 1986
- Alcohol and Aldehyde Dehydrogenase Isoenzymes in North American IndiansAlcohol, Clinical and Experimental Research, 1985
- Genetic Determinants of Alcohol and Aldehyde Dehydrogenases and Alcohol MetabolismSeminars in Liver Disease, 1981
- Alcohol dehydrogenase isozymes in adult human stomach and liver: evidence for activity of the ADH3 locusAnnals of Human Genetics, 1972