Individual specific DNA fingerprints from a hypervariable region probe: alpha-globin 3?HVR
- 1 June 1988
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 79 (2) , 142-146
- https://doi.org/10.1007/bf00280553
Abstract
A probe detecting a hypervariable region (HVR) 3′ to the alpha globin locus on chromosome 16 has been used to produce DNA fingerprints. Segregation analysis has revealed multiple, randomly dispersed DNA fragments inherited in a Mendelian fashion with minimal allelism and linkage. The fingerprints are highly polymorphic (probability of chance association between random individuals «10-14). The probe is, therefore, a powerful discriminating tool: it is envisaged that this probe will have forensic applications, including paternity cases, and will be informative in linkage analysis.This publication has 24 references indexed in Scilit:
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