Correlation Between Chemical Constitution and Capillary Activity of Adrenalocortical Hormones.
- 1 June 1956
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 92 (2) , 282-285
- https://doi.org/10.3181/00379727-92-22452
Abstract
To be able to increase capillary resistance a steroid must possess the same chemical structural prerequisites as required for anti-inflammatory properties. Alterations in cortisone molecule which potentiate its anti-inflammatory activity also increase capillary activity. It seems that capillary activity, as measured by the capillary resistance test, is intimately related with the mechanism involved in the anti-inflammatory effect. Capillary resistance test on adrenalectomized rat is proposed as a new bio-assay method for the demonstration of the anti-inflammatory activity of corticoids.Keywords
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