Rabies Group-Specific Ribonucleoprotein Antigen and a Test System for Grouping and Typing of Rhabdoviruses
- 1 May 1973
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 11 (5) , 748-755
- https://doi.org/10.1128/jvi.11.5.748-755.1973
Abstract
Cell-associated ribonucleoprotein (RNP) was isolated from BHK-21 cells infected with several strains of rabies and rabies-related viruses. The RNP-antigen from rabies and related viruses induced the formation of complement-fixing, precipitating, and immunofluorescent antibodies, and proved to be the group-specific antigen common to all rabies viruses. Antigens of the envelope which induce virus-neutralizing antibodies are apparently determinative for the serotype of a virus as evidenced by two-way neutralization tests. A combination of these methods seems to be a useful approach to the serological grouping and typing of rhabdoviruses.Keywords
This publication has 17 references indexed in Scilit:
- Characterization of Subviral Components Resulting from Treatment of Rabies Virus with Tri(n-butyl) PhosphateJournal of General Virology, 1972
- Isolation of a hemagglutinating, immunizing, and non-infectious subunit of the rabies virionArchiv für die gesamte Virusforschung, 1971
- Purification of rabies virus from tissue cultureArchiv für die gesamte Virusforschung, 1971
- Polypeptides of avian RNA tumor virusesVirology, 1970
- Biochemical and biophysical studies on the nucleocapsid and on the RNA of rabies virusVirology, 1969
- Tables for estimating sedimentation through linear concentration gradients of sucrose solutionAnalytical Biochemistry, 1967
- Rhinoviruses: a Numbering SystemNature, 1967
- Syrian Hamster Fibroblast Cell Line BHK21 and its DerivativesNature, 1964
- Determination of the base composition of deoxyribonucleic acid from its buoyant density in CsClJournal of Molecular Biology, 1962
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951