STRUCTURE AND RIBONUCLEOPROTEIN STAINING OF KINETOCHORES OF COLCHICINE-TREATED HELA-CELLS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 16  (3) , 480-484
Abstract
HeLa [Human cervical cancer] cells treated with colchicine show a lengthening of kinetochores lacking an inner layer. Combined EDTA and RNase treatment indicate the presence of ribonucleoprotein in the dense outer layer as well as in the surrounding fine fibrillar mass. Reconstructions from serial sections reveal a band-like enlargement of these layers around the primary constriction during the inhibition of mitosis by colchicine.