Studies on the Detection of Adverse Drug Reactions in the Newborn

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Abstract
The drugs taken by 67 consecutive private patients during the last trimester of pregnancy have been analyzed by means of a maternal diary composed of a day-by-day medication record. Each mother took an average of 8.7 drugs during the period of study (three to nine weeks), when the drugs contained in multiple drug combinations are included. An average of 6.9 (80%) of these were taken without medical supervision or knowledge, and 1.8 (20%) were specifically ordered by the doctor. Next to vitamins, the most commonly used drugs were aspirin (69% of patients) and antacids (60% of patients). By using a personal medication record, the intake of drugs including those not ordinarily considered as "medicines" can be assessed in an outpatient population.

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