Temporal Trends in the Use of Anticoagulants Among Older Adults With Atrial Fibrillation

Abstract
COMPARED WITH placebo, warfarin sodium treatment dramatically reduces the risk of stroke, systemic embolisms, and death in persons with atrial fibrillation.1-5 The benefits of aspirin treatment—with or without fixed-dose warfarin—are less pronounced than those of adjusted-dose warfarin6,7 but are nonetheless significant.1,3,8