Haptoglobin concentrations in children aged 9–10 years and its correlation to indirect parameters of erythrocyte turnover

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Abstract
Low serum haptoglobin values are often found in children. Nine different parameters were studied in 125 healthy children aged 9-10 yr to get indirect information on erythrocyte turnover and its possible relation to the low mean plasma haptoglobin level in childhood. The mean LD [lactate dehydrogenase] activity was higher than in adults. The mean HbCO% saturation (HbCO%) and the mean serum haptoglobin concentrations were lower than in adults. No significant correlation was found between serum haptoglobin and serum Fe, serum bilirubin and HbCO%. Significant correlation at low r-values was found between serum Fe, serum bilirubin and HbCO%. The low serum haptoglobin levels often seen in children seemed not to be caused by an increase in erythrocyte turnover.

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