The Prognostic Significance of p53 Expression Quantitated by Computerized Image Analysis in Epithelial Ovarian Cancer
- 1 January 1999
- journal article
- research article
- Published by Wolters Kluwer Health in International Journal of Gynecological Pathology
- Vol. 18 (1) , 42-51
- https://doi.org/10.1097/00004347-199901000-00006
Abstract
The prognostic significance of p53 expression in 316 archival epithelial ovarian cancers was assessed using a static, computer-aided image analysis system (CAS 200). Using a 10% cut-off point, 26% of primary tumors and 35% of their metastases were positive for p53 protein. p53 positivity closely correlated with tumor grade (p 2 cm were significant predictors of poor overall survival. In both the overall (pKeywords
This publication has 0 references indexed in Scilit: