The isthmic Oviduct of the Ewe: What is the Biological Significance of High Affinity Cytosoi Receptors for Estradiol and Progesterone?

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Abstract
By 36 h after estradiol (E2) injection, the level of cytosol receptors for E2 and progesterone (P) in whole isthmic oviduct of the ewe was, respectively, 67 and 50% higher than in control animals. The effect of E2 and P alone and in various combinations on protein synthesis and mean cell RNA content in this tissue was also measured. E2 stimulated both parameters whereas P alone or in combination with E2 was without real effect. The relative roles of the 2 receptor proteins in the ovine isthmic oviduct are discussed.