Lichen plan us and liver disease: how strong is the association?

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Abstract
Patients (113) with histologically confirmed oral lichen planus, were examined for evidence of liver disease. No patient had clinical evidence of liver disease. Nine patients (7.9%) had a raised serum concentration of a single enzyme; 6 patients had raised .gamma.-glutamyl transpeptidase, 2 had raised alkaline phosphatase and 1 had raised aspartate transaminase levels. No patient had serum auto-antibodies suggestive of primary biliary cirrhosis or chronic active hepatitis. Most patients presenting with oil lichen planus are unlikely to have liver disease.

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