Negative result of short-term genotxicity tests with 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene
- 1 July 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 11 (7) , 1153-1157
- https://doi.org/10.1093/carcin/11.7.1153
Abstract
The phenobarbital-like enzyme inducer and tumor promoter of murine hepatocarcinogenesis, 1 ,4-bis[2-(3,5-dichloro-pyridyloxy)]benzene has been assayed in short-term genotoxicity tests, i.e. the Salmonella mutagenicity test, micronucleus and chromosomal aberrations analysis in mouse bone marrow cells in vivo, DNA alkaline elution and DNA unwinding assays in mouse liver in vivo. All the assays performed proved negative.This publication has 2 references indexed in Scilit:
- The induction of micronuclei as a measure of genotoxicityMutation Research/Reviews in Genetic Toxicology, 1983
- SPECIES-DIFFERENCES IN RESPONSIVENESS TO 1,4-BIS[2-(3,5-DICHLOROPYRIDYLOXY)]-BENZENE, A POTENT PHENOBARBITAL-LIKE INDUCER OF MICROSOMAL MONO-OXYGENASE ACTIVITY1981