The enhancing effect of multiple sclerosis brain homogenates on the active E rosette forming lymphocytes
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Zeitschrift für Neurologie
- Vol. 218 (4) , 245-251
- https://doi.org/10.1007/bf00312880
Abstract
Lymphocytes from 15 of 17 patients with clinically well defined multiple sclerosis (MS) responded to all four MS brain homogenates as assayed by active E rosette test. Lymphocytes from only one neurological patient, out of 18 tested, responded to MS brain homogenates. The nature of the stimulating agent from MS brains remains to be determined. Lymphocyten von Patienten mit klinisch gesicherter Multipler Sklerose reagierten in 15 von 17 Fällen je mit 4 Homogenaten von MS-Gehirnen im aktiven E-Rosetten-Test. Nur bei einem von 18 Patienten mit anderen neurologischen Leiden reagierten die Lymphocyten auf MS-Gehirnhomogenate. Die genaue Natur des stimulierenden Agens im MS-Gehirn ist noch unbekannt.Keywords
This publication has 9 references indexed in Scilit:
- Cellular immune responses in Huntington's disease (H.D.)Cellular Immunology, 1977
- Correlation between active rosette formation and delayed cutaneous hypersensitivity in experimental allergic encephalomyelitisNeurochemical Research, 1977
- Antigen-stimulated rosette formation by T lymphocytes in experimental allergic encephalomyelitisNeurochemical Research, 1977
- The Active E-Rosette Test: A Sensitive in Vitro Correlate for Human Delayed-Type HypersensitivityThe Journal of Immunology, 1977
- Multiple sclerosis-associated agent: transmission to animals and some properties of the agentInfection and Immunity, 1975
- A modified assay for the detection of human adult active rosette forming lymphocytesJournal of Immunological Methods, 1975
- No Mouse PMN Leukocyte Depression after Inoculation with Brain Tissue from Multiple Sclerosis or Spongiform EncephalopathiesNature, 1974
- DECREASED PERCENTAGE OF POLYMORPHONUCLEAR NEUTROPHILS IN MOUSE PERIPHERAL BLOOD AFTER INOCULATION WITH MATERIAL FROM MULTIPLE SCLEROSIS PATIENTSThe Journal of Experimental Medicine, 1972
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951