CHARACTERIZATION OF TIN-TECHNETIUM COLLOID IN TECHNETIUM-LABELED ALBUMIN PREPARATIONS

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 19  (4) , 387-392
Abstract
The 99mTc human serum albumin (HSA) system was reinvestigated with gel filtration as the assay method. Other than 99mTc HSA, 2 radioactive components were isolated by this technique. Both components are tin-technetium colloids of differing particle sizes, and the relative quantity of each one is pH-dependent. The colloid was further characterized by protein-induced X-ray emission analysis (PIXE) and by tissue distribution in rats. By this gel-filtration method, commercial 99mTc HSA kits were evaluated and have revealed varying amounts of colloids present.

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