Synthesis and stereomutation of optically active α-cyanosulphoxides
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- p. 614-617
- https://doi.org/10.1039/p19810000614
Abstract
Reaction of (–)-menthyl(S)-toluene-p-sulphinate with nitriles and lithium NN-di-isopropylamide (LDA) in 1:1:1 and 1:2:1 ratios affords optically active α-cyano- and α-cyano-β-imino-sulphoxides, respectively. α-Cyanobenzyl sulphoxide racemizes through a homolytic process in a temperature range (35–50 °C) well below that required for benzyl aryl sulphoxides.Keywords
This publication has 0 references indexed in Scilit: