Complications of intravenous DSA performed for carotid artery disease: a prospective study.

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Abstract
Patients (102) who were being evaluated for carotid artery disease, were prospectively studied for complications occurring as a result of i.v. digital subtraction angiography (DSA) [using Renografin-76]. The type, number and outcome of complications were recorded. The amount of contrast material used, along with the patient''s age and medical history were reviewed for possible correlation with increased complications. There were 55 total complications or side effects involving 37 patients. CNS complications included 6 major-transient and 1 major-permanent complication. Systemic complications included 20 major-transient and 2 major-permanent events. The patient''s age and the amount of contrast material used did not appear to be significant risk factors. Complications in this series were significantly higher than previous DNA reports and published data on conventional angiography studies. Many of these patients were in a relatively high risk group, including 74 patients who had multisystem disease and 30 who had histories of angina.

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