Induction of Tolerance to Skin Homografts in Rabbits by Alterations of Placental Permeability.,
- 1 January 1963
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 112 (1) , 136-138
- https://doi.org/10.3181/00379727-112-27972
Abstract
Administration of hyaluronidase and/or histamine in high doses to pregnant rabbits from the 11th to the 30th day of gestation resulted in approximately 25% of the progeny being completely tolerant and an additional 30% partially tolerant to maternal skin grafts. Furthermore, complete tolerance to skin grafts of their progeny was induced in 28% and partial tolerance in an additional 34% of the injected does under these experimental conditions.Keywords
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