Effect of Mouthrinsing after Toothbrushing with a Fluoride Dentifrice on Human Salivary Fluoride Levels

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Abstract
In a recent clinical trial of sodium monofluorophosphate dentifrices, oral rinsing habits were found to influence dental caries. Thus an oral fluoride clearance study has been undertaken which was designed to test a possible mechanism for the observed effects. Eight subjects brushed with one of the trial dentifrices and then rinsed using 1 of 8 procedures of varying thoroughness. The salivary fluoride concentration measured 5 min after dentifrice application decreased significantly with increasing rinse volume, rinse duration, and rinse frequency (p < 0.01, analysis of variance). The area under the clearance curve determined over a further 3 h was significantly higher (300%; p < 0.01) following use of the least thorough rinsing procedure (5 ml × 2 s once) as compared with the corresponding area under the clearance curve following the most thorough procedure (20 ml × 10 s twice). These findings indicate that rinsing habits may play an important role in the oral retention of fluoride from dentifrices which may, in turn, affect their clinical efficacy.

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